Short answer

Am I a candidate for HIFU?

That question can only be answered reliably through an imaging-based physician assessment. Candidacy is judged from your fibroids’ size, number, type, location and MRI tissue characteristics, together with your general health and pregnancy plans. Nothing on the internet — including this page — replaces that assessment.

The situations where HIFU performs well are as well defined as the situations where it should not be used. This page describes both, as they are.

Factors considered in the assessment

Fibroid size and number

Very small fibroids usually need no treatment at all; with very large or numerous fibroids, reaching sufficient ablation in a single session becomes harder. Clinical studies have mostly enrolled fibroids within certain size ranges; what range matters for you becomes clear in the physician review.

Fibroid type and location

Fibroids are classified by their position in the uterine wall (the international FIGO classification). Fibroids within the wall are frequently assessed for HIFU, while pedunculated fibroids — attached by a stalk — have generally been excluded in clinical studies. Location also determines whether the ultrasound beam can reach the target through a safe path.

MRI tissue characteristics

Evidence
T2 signal characteristics on MRI are important predictors of ablation success: in studies, fibroids that appear dark (hypointense) respond better to heat treatment, while bright (hyperintense) fibroids carry a markedly higher retreatment risk.

This is why MRI sits at the centre of the eligibility assessment.

Source: 2024 · International Journal of Hyperthermia2022 · International Journal of Hyperthermia

General health and pregnancy plans

The procedure requires lying prone for an extended period, which some patients cannot tolerate. For patients planning pregnancy, method selection needs particular care: data on pregnancy after HIFU are limited and partly conflicting, and this deserves a frank discussion with your physician.

When is HIFU usually not appropriate?

The following are common exclusion criteria in clinical studies; the final decision is always individual:

  • Pregnancy
  • Suspected malignancy (diagnosis comes first, not ablation)
  • Pedunculated fibroids
  • Extensive scarring, bowel or other obstacles in the beam path
  • Inability to lie prone for the duration of the procedure
  • Degenerated fibroids that have already lost their blood supply
Evidence
Patient selection is one of the strongest determinants of both the safety and the long-term success of HIFU; in well-selected patients, retreatment rates are markedly lower.

Source: 2024 · International Journal of Hyperthermia2011 · NICE (İngiltere Ulusal Sağlık ve Bakım Mükem

What if you are not a candidate?

Not being suitable for HIFU does not mean going untreated. Myomectomy, embolisation and other options are strong alternatives for different situations — and if the assessment finds HIFU unsuitable, those options are explained to you openly. Our aim is not to deliver HIFU; it is to help you identify the right treatment for your situation.

Have your case assessed

If you already have an MRI or ultrasound report, the review is faster. The assessment does not replace a medical decision; it gathers the information a physician needs.

You can share your imaging and ask your questions.

Start a HIFU eligibility assessment